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Image Search Results
Journal: Nature reviews. Drug discovery
Article Title: Antibodies and venom peptides: New therapeutic modalities for ion channels
doi: 10.1038/s41573-019-0013-8
Figure Lengend Snippet: Figure illustrating the size relation of a full-length immunoglobulin G (IgG2a, pdb: 11GT, ribbon presentation) colored in orange, an antigen-binding fragment (Fab, pdb: 1K4C) colored in orange, a KnotBody Fab colored in green, and a nanobody (pdb: 6C5W) colored in pink. The Ecballium elaterium Trypsin Inhibitor (EETI-II) structure within the KnotBody is shown in space-filling representation. The Kv channel structure is based on the Kv1.2-Kv2.1 chimera196 (pdb: 2R9R) and shown in ribbon representation and colored in beige. Potassium ions within the selectivity filter region are shown in sphere representation and colored in purple.
Article Snippet: We thank Aneesh Karatt Vellatt at
Techniques: Binding Assay